Vaccine Mandates for Nurses: Where Major U.S. Healthcare Systems Stand

Vaccine Mandates for Nurses: Where Major U.S. Healthcare Systems Stand

Vaccine Mandates for Nurses: Where Major U.S. Healthcare Systems Stand

As COVID-19 continues to severely impact millions globally, numerous healthcare systems across the United States have enforced vaccination mandates for their nurses and other staff members.

Hospitals that have implemented these mandates argue that the vaccines are the most effective way to ensure the safety of both employees and patients, particularly in light of recent increases in COVID-19 hospitalizations. Additionally, staffing shortages have remained a significant challenge for healthcare systems, which may influence some organizations’ decisions to mandate vaccinations.

In November 2021, an emergency regulation was released by the administration mandating COVID-19 vaccinations for all healthcare workers nationwide. However, this mandate has faced legal challenges in various states, leaving the future of this federal requirement uncertain.

Status of Vaccine Mandates in U.S. Healthcare Systems

Please note that policies regarding COVID-19 vaccinations are rapidly changing. While we've made every effort to compile the most recent information from some of the largest healthcare systems, we cannot guarantee its accuracy. Always confirm with your employer, local healthcare providers, or governmental entities for specific guidelines.

Vaccine Mandate Status for Major U.S. Healthcare Systems
Updated in 2025

StateHospital or Health SystemVaccine Mandate StatusDeadlineSource Link
MississippiForrest General HospitalNot requiredN/ASource
NebraskaBryan Medical CenterRequiredNot listedSource
PennsylvaniaUniversity of Pennsylvania Health System (UPHS)RequiredCurrent dateSource
FloridaAdventHealth-OrlandoNo (paused)N/ASource
IllinoisNorthwestern Memorial HospitalRequiredCurrent dateSource
ArkansasArkansas Children’s HospitalRequiredCurrent dateSource
CaliforniaUCLA Medical CenterRequiredCurrent dateSource
ColoradoUCHealth University of Colorado HospitalRequiredCurrent dateSource
ConnecticutYale New Haven HospitalRequiredCurrent dateSource
District of ColumbiaChildren's National HospitalRequiredCurrent dateSource
FloridaUF Health Shands HospitalRequiredCurrent dateSource
HawaiiQueen's Medical CenterRequiredCurrent dateSource
IndianaMayo ClinicRequiredCurrent dateSource
KentuckyNorton HealthcareRequiredCurrent dateSource
LouisianaOur Lady of the Lake Regional Medical CenterPausedN/ASource
MaineMaine Medical CenterRequiredCurrent dateSource
MarylandJohns Hopkins HospitalRequiredCurrent dateSource
MassachusettsMassachusetts General Hospital-BrighamRequiredCurrent dateSource
MinnesotaMayo ClinicRequiredCurrent dateSource
MissouriBarnes-Jewish HospitalRequiredCurrent dateSource
New YorkNewYork-Presbyterian HospitalRequiredCurrent dateSource
OhioCleveland ClinicRequiredCurrent dateSource
TennesseeHCA HealthcareNot requiredN/ASource

Does GoodWork Health require nurses to be vaccinated?

Currently, GoodWork Health does not require nurses to provide their vaccination status on our platform. However, nurses should be aware that many of our affiliated hospitals, such as those listed above, have vaccine mandates in place. Nurses must follow these policies when accepting employment with those facilities.


Find Healthcare Job Opportunities Near You

If you are looking for healthcare job openings, including roles that may or may not require vaccination, you can explore a variety of positions and learn more about the requirements at GoodWork.

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